So… I’m waffling a bit on which classes are best to replicate the Three Sciences. I’ve now done a bit more research on the classes that have been released outside the PHB and it looks like the best fits are probably.

Astronomy: Warlock (Striker/Controller)
Cartography: Warden (Defender/Controller)
Anthropology: Artificer (Leader/Controller)

The main problem being that the Artificer is only released in a playtest version and won’t see the light of day until the Eberron Player’s Guide comes out in July. Also, neither the Warden or Artificer are included in the GSL and there’s no way of knowing if they are likely to be. I suppose I could create entirely new classes that resemble existing classes in some ways, but that seems like a lot of unnecessary work. Hmm…